New article: “Peptideins: Navigating the gray zone of the proteome”

Summary:

Translated sequences are often treated as either genes or noise. A recent TransCODE Consortium study by Deutsch et al. introduces peptideins: endogenous proteins with evidence of synthesis but an unresolved biological status. This concept offers a cautious way to expand the human proteome while preserving the distinction between translation, molecular detection, and function.

Article data:

Giulia Pesce and Salvador Ventura. Peptideins: Navigating the gray zone of the proteome. Trends in Biochemical Sciences, 2026. ISSN 0968-0004. https://doi.org/10.1016/j.tibs.2026.06.004.

DOI:10.1016/j.tibs.2026.06.004