Digestive, Cognitive and Hedonic Responses to a Meal
The digestive system may induce symptoms if something is going wrong. We hypothesized that the gut can also originate pleasant sensations, and our aim was demonstrate the hedonic component of the digestive response to a meal.
We performed a study in healthy subjects measuring the digestive (gastric relaxation), cognitive (perception of satiation, fullness) and hedonic responses (digestive well-being as satisfaction/dissatisfaction) to a 240 mL probe meal (either 12 kcal broth or water as inert control) ingested at controlled conditions. Experiments were performed under normal conditions and with experimental induction of symptoms (fullness) mimicking a distorted digestive function.
|Figure 1. Meal ingestion induces metered digestive responses, as well as conscious sensations; depending on the characteristics of the meal and the digestive response, perception may have a pleasant or unpleasant dimension.|
In conclusion, in normal conditions meal ingestion induces satisfaction and a pleasant sensation; furthermore, meal ingestion also improves aversive sensations induced by experimental distortion of digestive function.
Malagelada, C.; Accarino, A.; Molne, L.; Mendez, S.; Campos, E.; Gonzalez, A.; Malagelada, J. R.; Azpiroz, F. Digestive, cognitive and hedonic responses to a meal. Neurogastroenterology & Motility. 2015, vol. 27, num. 3, p. 389-396. doi: 10.1111/nmo.12506.