University master's degrees
Erasmus Mundus Master's Degree in Human Diseases Models Morphological Phenotyping (MorphoPHEN)

Do you want to leave a mark in human disease reseach? This unique in all Europe training programme will give you the in deep knowledge to improve your skills in preclinical biomedicine

Content Official Master's Degree in Erasmus Mundus in Human Diseases Models Morphological Phenotyping (MorphoPHEN)

Knowledge

  • Understand the mechanisms that control mouse embryonic processes.
  • Identify and understand the shape, structure, arrangement, and relationships of mouse organs.
  • Identify mouse tissues and organs microscopically.
  • Understand the fundamental principles of mouse pathology and identify organ structural abnormalities by histology and immunohistochemistry. Understand the anatomical basis for diagnostic imaging of the mouse.
  • Recognize the basic principles of radiological protection, anaesthesia, and mouse handling.
  • Understand the principles of the most relevant preclinical imaging techniques and their application in biomedicine.
  • Understand the fundamental principles and recognize the main tools established for deep learning.
  • Understand the ethical (3Rs), quantitative and improvement in reproducibility (ARRIVE) aspects in animal experimentation.
  • Specific knowledge related to the objective and content of the master's thesis.

Skills

  • Correctly use anatomical, pathological, imaging, and deep learning terminology.
  • Perform dissection and necropsy of a mouse correctly.
  • Interpret data, image processing and post-processing techniques for the different preclinical imaging modalities.
  • Apply imaging knowledge to accurately demonstrate through images the anatomy and structure of all mouse organs.
  • Use deep learning architectures in real problems, including detection and recognition of patterns on images and 1D signals, diagnosis, and decisions.
  • Apply quantitative statistical methods to the design of experiments with mice.
  • Writing a research article: extracting key information from the existing bibliography, planning, and structuring a manuscript.

 

Competences

  • Ability to integrate mouse morphology through the organic, cellular, and subcellular levels.
  • Ability to correlate structural alterations of mouse organs with specific pathological processes.
  • Ability to compare different imaging methodologies and choose the most appropriate for a specific mouse phenotypic analysis.
  • Ability to evaluate the performance of deep learning methods.
  • Ability to correctly design experiments with mice.
  • Being able to design a research plan on the different mouse morphological phenotyping methodologies, describing the definition of the problem, the hypothesis, the research objectives, and the research questions in relation to the relevant literature.